Ontology consolidation in bioinformatics

نویسندگان

  • Sven Hartmann
  • Henning Köhler
  • Jing Wang
چکیده

Ontologies enjoy increasing popularity among bioinformatics researchers who seek assistance in coping with the rapid upgrowth of biological data to be handled and related information to be considered. While communities of committed ontology pioneers drive the development and optimisation of ontologies for a wide range of relevant domains, the amble adoption of ontologies in bioinformatics research is still decelerated by technological, managerial and communication barriers. This paper contains a brief review of current trends, challenges and perspectives in ontology research and practice in bioinformatics.

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Computational prediction of miRNAs in Nipah virus genome reveals possible interaction with human genes involved in encephalitis

Current re-emergence of Nipah virus (NiV) in India caused 11 deaths so far and many patients were kept in quarantine. A thorough study of previous outbreaks occurred in Malaysia, Bangladesh and India represents cases with high rate of fatality due to acute encephalitis. Our work involves genome analysis of NiV for prediction of miRNAs and their targeted genes in human in order to understand enc...

متن کامل

Evaluation of Ontology Merging Tools in Bioinformatics

Ontologies are being used nowadays in many areas, including bioinformatics. One of the issues in ontology research is the aligning and merging of ontologies. Tools have been developed for ontology merging, but they have not been evaluated for their use in bioinformatics. In this paper we evaluate two of the most well-known ontology merging tools with a bioinformatics perspective. As test ontolo...

متن کامل

Evaluation of ontology development tools for bioinformatics

Ontologies are being used nowadays in many areas, including bioinformatics. To assist users in developing and maintaining ontologies a number of tools have been developed. In this paper we compare four such tools, Protégé-2000, Chimaera, DAG-Edit and OilEd. As test ontologies we have used ontologies from the Gene Ontology Consortium. No system is preferred in all situations, but each system has...

متن کامل

Modeling Strategic Partnerships Using the E3value Ontology: A Field Study in the Banking Industry

The banking industry is subject to a wave of consolidation taking the form of mergers but also the formation of strategic partnerships. In this chapter, we present how such a partnership can be assessed using the e3value ontology. This ontology allows us to model networks of enterprises and partnerships, exchanging things of economic with each other. To adequately model strategic partnerships, ...

متن کامل

Fractionation, rearrangement and subgenome dominance

MOTIVATION Fractionation is arguably the greatest cause of gene order disruption following whole genome duplication, causing severe biases in chromosome rearrangement-based estimates of evolutionary divergence. RESULTS We show how to correct for this bias almost entirely by means of a 'consolidation' algorithm for detecting and suitably transforming identifiable regions of fractionation. We c...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

عنوان ژورنال:

دوره   شماره 

صفحات  -

تاریخ انتشار 2010